HitPredict

Interactor 1: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Interactor 2: GRIK2 (P39087)
Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Glutamate receptor beta-2) (GluR beta-2)
Gene: GRIK2

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.39 1.00 0.625

The method score is based on:

Property Details
Experiments 10862698
Identification Methods affinity chromatography technology, coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd, Lig_chan~SBP_bac_3, Lig_chan-Glu_bd~SBP_bac_3
Common GO terms GO:0004970 - glutamate-gated receptor activity
GO:0005886 - plasma membrane
GO:0006874 - intracellular calcium ion homeostasis
GO:0007268 - chemical synaptic transmission
GO:0014069 - postsynaptic density
and 17 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 938
Mm

1 908
+ Rn
+ Rn
+ Hs
+ Mm
+ Mm
+ Rn
+ Rn
+ Hs
+ Rn
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024