HitPredict

Interactor 1: DRD3 (P35462)
D(3) dopamine receptor (Dopamine D3 receptor)
Gene: DRD3

Interactor 2: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25517094
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 400 Hs			1 368
+	Hs
		723749 DRD3_HUMAN (1-400): 8.17e-97: 296: 100.00		SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30
+	Hs
		723748 DRD3_HUMAN (1-400): 8.17e-97: 296: 100.00		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		445809 ADA2A_HUMAN (1-399): 2.81e-73: 238: 29.91		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		436884 ACM2_HUMAN (30-400): 1.3e-72: 236: 22.78		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		534049 ADRB3_HUMAN (43-394): 2.61e-72: 233: 31.04		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		445811 ADA2A_HUMAN (1-399): 2.81e-73: 238: 29.91		SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30
+	Hs
		534051 ADRB3_HUMAN (43-394): 2.61e-72: 233: 31.04		SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30
+	Hs
		574791 ADA2B_HUMAN (38-399): 2.32e-69: 227: 26.76		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		445810 ADA2A_HUMAN (1-399): 2.81e-73: 238: 29.91		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Mm
		897202 DRD2_MOUSE (9-400): 1.46e-73: 238: 44.50		SH3G2_MOUSE (1-368): 8.98e-84: 260: 69.02
+	Hs
		436885 ACM2_HUMAN (30-400): 1.3e-72: 236: 22.78		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		534050 ADRB3_HUMAN (43-394): 2.61e-72: 233: 31.04		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		574792 ADA2B_HUMAN (38-399): 2.32e-69: 227: 26.76		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		436947 ACM4_HUMAN (3-400): 5.91e-61: 206: 20.64		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		1307428 HRH3_HUMAN (43-399): 1.84e-59: 201: 23.96		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		436949 ACM4_HUMAN (3-400): 5.91e-61: 206: 20.64		SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30
+	Hs
		436948 ACM4_HUMAN (3-400): 5.91e-61: 206: 20.64		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		1307445 HRH3_HUMAN (43-399): 1.84e-59: 201: 23.96		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		723735 DRD3_HUMAN (1-400): 8.17e-97: 296: 100.00		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Dm
		993225 MOODY_DROME (13-400): 5.1e-57: 199: 18.43		GRAP_DROME (301-360): 1.2e-10: 62.4: 48.33