Interactor 1: ACTN2 (P35609)
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)
Gene: ACTN2
Interactor 2: ACTN3 (Q08043)
Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein)
Gene: ACTN3
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 1.00 | 0.747 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9675099 |
| Identification Methods | far western blotting, pull down, affinity chromatography technology |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CH~CH, CH~EFhand_Ca_insen, CH~Spectrin, CH~EF-hand_7, EF-hand_7~EFhand_Ca_insen, EFhand_Ca_insen~EFhand_Ca_insen, EFhand_Ca_insen~Spectrin, Spectrin~Spectrin |
| Common GO terms | GO:0005178 - integrin binding GO:0005509 - calcium ion binding GO:0005829 - cytosol GO:0005884 - actin filament GO:0005925 - focal adhesion and 13 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
