HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: SMD2 (P62316)
Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2)
Gene: SNRPD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	25192599, 29884807, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008380 - RNA splicing
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 118
+	Hs
		912528 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		SMD2_HUMAN (1-118): 6.33e-44: 140: 100.00
+	Hs
		912429 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		SMD2_HUMAN (1-118): 6.33e-44: 140: 100.00
+	Hs
		912591 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		SMD2_HUMAN (1-118): 6.33e-44: 140: 100.00
+	Hs
		212123 HTSF1_HUMAN (267-372): 6.19e-23: 104: 21.30		SMD2_HUMAN (1-118): 6.33e-44: 140: 100.00
+	Sc
		376893 PABP_YEAST (263-381): 1.57e-10: 65.5: 18.49		LSM3_YEAST (26-109): 2.43e-20: 80.1: 27.38