HitPredict

Interactor 1: SOX6 (P35712)
Transcription factor SOX-6
Gene: SOX6

Interactor 2: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 828 Hs			1 2157
+	Hs
		727710 SOX5_HUMAN (1-789): 5.72e-135: 421: 55.79		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		727951 SOX6_HUMAN (1-828): 0: 640: 100.00		NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40
+	Hs
		727947 SOX6_HUMAN (1-828): 0: 640: 100.00		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		820897 SSRP1_HUMAN (257-792): 1.33e-37: 152: 12.45		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		727910 SOX6_HUMAN (1-828): 0: 640: 100.00		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		818122 SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		727832 SOX5_HUMAN (1-789): 5.72e-135: 421: 55.79		NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40
+	Hs
		727830 SOX5_HUMAN (1-789): 5.72e-135: 421: 55.79		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		152602 SOX5_HUMAN (1-789): 5.72e-135: 421: 55.79		KMT2D_HUMAN (411-984): 1.99e-09: 65.4: 19.37
+	Hs
		727788 SOX5_HUMAN (1-789): 5.72e-135: 421: 55.79		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		233821 HBP1_HUMAN (515-703): 1.53e-36: 146: 23.28		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		807628 SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		996965 SSRP1_HUMAN (257-792): 1.33e-37: 152: 12.45		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		818226 SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02		ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15
+	Hs
		990941 TF7L2_HUMAN (327-801): 6.75e-37: 149: 12.07		ZO1_HUMAN (265-982): 3.45e-30: 133: 13.23
+	Hs
		1056996 TF7L2_HUMAN (327-801): 6.75e-37: 149: 12.07		MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22
+	Hs
		817913 SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02		MAP1A_HUMAN (389-2155): 2.3e-14: 81.6: 8.60
+	Hs
		1343280 TF7L2_HUMAN (327-801): 6.75e-37: 149: 12.07		CABIN_HUMAN (211-1108): 5.1e-10: 67.2: 11.31
+	Hs
		996845 SSRP1_HUMAN (257-792): 1.33e-37: 152: 12.45		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		152610 SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02		KMT2D_HUMAN (411-984): 1.99e-09: 65.4: 19.37