Protein: M3K9
Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)

Gene: M3K9, MAP3K9
Organism: Homo sapiens
Interactions: 34
UniProt ID: P80192

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004706 - JUN kinase kinase kinase activity
GO:0004708 - MAP kinase kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

968629

NCS1
Neuronal calcium sensor 1

2

12

High-throughput

0.811

High

461354

HS90A
Heat shock protein HSP 90-alpha

2

19

High-throughput

0.789

High

1009756

HPCA
Neuron-specific calcium-binding protein hippocalcin

2

12

High-throughput

0.789

High

789629

HPCL1
Hippocalcin-like protein 1

2

12

High-throughput

0.705

High

274533

DNJB6
DnaJ homolog subfamily B member 6

1

3

High-throughput

0.691

High

1009762

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

18

High-throughput

0.691

High

468264

HS90B
Heat shock protein HSP 90-beta

1

19

High-throughput

0.665

High

603235

KPCA
Protein kinase C alpha type

1

3

High-throughput

0.665

High

679129

DNJB1
DnaJ homolog subfamily B member 1

1

0

High-throughput

0.656

High

1009767

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.656

High

966191

1433G
14-3-3 protein gamma

2

20

High-throughput

0.621

High

971400

1433E
14-3-3 protein epsilon

1

8

High-throughput

0.554

High

341019

DIRA3
GTP-binding protein Di-Ras3

1

2

High-throughput

0.553

High

690900

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

729743

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

990091

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1009757

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1009769

WDR6
tRNA

1

1

High-throughput

0.536

High

1009771

CHIP
E3 ubiquitin-protein ligase CHIP

1

4

High-throughput

0.536

High

1009759

SETB1
Histone-lysine N-methyltransferase SETDB1

1

4

High-throughput

0.515

High

1009764

LMO3
LIM domain only protein 3

1

4

High-throughput

0.515

High

1009765

KAT5
Histone acetyltransferase KAT5

1

1

High-throughput

0.515

High

1009768

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

9

Small-scale

0.501

High

323700

AP2A2
AP-2 complex subunit alpha-2

1

5

High-throughput

0.489

High

344668

AP2A1
AP-2 complex subunit alpha-1

1

5

High-throughput

0.489

High

483323

CLCB
Clathrin light chain B

1

2

High-throughput

0.489

High

1009758

EPN4
Clathrin interactor 1

1

1

High-throughput

0.489

High

1009766

AP2M1
AP-2 complex subunit mu

1

5

High-throughput

0.489

High

1009772

MAGD2
Melanoma-associated antigen D2

1

1

High-throughput

0.489

High

730506

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

1009763

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

1009770

S22AB
Solute carrier family 22 member 11

1

1

High-throughput

0.407

High

1009760

SEPT7
Septin-7

1

0

High-throughput

0.269

Low

1009761

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025