HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 2527
+	Hs
		409102 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		110755 H6VRG1_HUMAN (143-509): 1.67e-112: 353: 71.94		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130283 K2C73_HUMAN (1-598): 8.9e-92: 296: 51.00		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		72923 B4DN72_HUMAN (72-557): 1.03e-86: 281: 44.15		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		531584 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		380486 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		3119 A0A0S2Z428_HUMAN (5-510): 8.33e-78: 259: 61.22		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1001518 Q0IIN1_HUMAN (58-509): 4.01e-66: 229: 61.50		LRRK2_HUMAN (1-2527): 0: 3008: 99.72