Interactor 1: BTK (P35991)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase) (Kinase EMB)
Gene: BTK
Interactor 2: PLCG2 (Q8CIH5)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-gamma-2) (PLC-gamma-2)
Gene: PLCG2
Species: Mus musculus
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19150402 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~SH3_1, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, C2~SH2, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1 |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0032496 - response to lipopolysaccharide GO:0032755 - positive regulation of interleukin-6 production GO:0032760 - positive regulation of tumor necrosis factor production and 6 others more... |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
