HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	37207277, unassigned3799
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1343
+	Hs
		971901 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		104490 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Mm
		104500 1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		971630 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		DAB2P_HUMAN (97-1342): 0: 778: 46.78
+	Hs
		729929 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		DAB2P_HUMAN (97-1342): 0: 778: 46.78
+	Hs
		990337 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DAB2P_HUMAN (97-1342): 0: 778: 46.78
+	Hs
		972106 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		NGAP_HUMAN (84-1341): 0: 731: 42.62
+	Hs
		730336 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		NGAP_HUMAN (84-1341): 0: 731: 42.62
+	Hs
		729670 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		IQGA1_HUMAN (219-857): 5.22e-123: 421: 13.35
+	Hs
		971539 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		GAPD1_HUMAN (412-1051): 3.03e-122: 417: 13.70
+	Hs
		729847 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		GAPD1_HUMAN (412-1051): 3.03e-122: 417: 13.70
+	Hs
		862793 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		IQGA1_HUMAN (219-857): 5.22e-123: 421: 13.35
+	Hs
		990238 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		GAPD1_HUMAN (412-1051): 3.03e-122: 417: 13.70
+	Hs
		971741 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		RASL3_HUMAN (182-865): 5.31e-111: 376: 35.91
+	Hs
		990453 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		RASL3_HUMAN (182-865): 5.31e-111: 376: 35.91
+	Hs
		637877 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		NF1_HUMAN (408-712): 3.22e-82: 301: 23.21
+	Hs
		637853 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		NF1_HUMAN (408-712): 3.22e-82: 301: 23.21
+	Mm
		972208 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		NF1_MOUSE (408-712): 4.17e-82: 300: 23.51
+	Hs
		637880 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		NF1_HUMAN (408-712): 3.22e-82: 301: 23.21
+	Mm
		989954 1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02		NF1_MOUSE (408-712): 4.17e-82: 300: 23.51