HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: TRI62 (Q9BVG3)
E3 ubiquitin-protein ligase TRIM62 (EC 2.3.2.27) (Tripartite motif-containing protein 62)
Gene: TRIM62

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 475
+	Hs
		623136 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		RO52_HUMAN (5-475): 2.87e-148: 433: 28.54
+	Hs
		623235 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		RO52_HUMAN (5-475): 2.87e-148: 433: 28.54
+	Hs
		730670 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		TRI68_HUMAN (1-473): 8.7e-135: 399: 28.34
+	Hs
		623259 1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66		RO52_HUMAN (5-475): 2.87e-148: 433: 28.54
+	Hs
		971641 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		TRI68_HUMAN (1-473): 8.7e-135: 399: 28.34
+	Hs
		990700 1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66		TRIM7_HUMAN (6-460): 9.54e-124: 372: 27.69
+	Hs
		623116 1433T_HUMAN (1-238): 1e-107: 312: 71.85		RO52_HUMAN (5-475): 2.87e-148: 433: 28.54
+	Hs
		623228 1433G_HUMAN (1-242): 1.87e-98: 289: 65.16		RO52_HUMAN (5-475): 2.87e-148: 433: 28.54
+	Hs
		194777 1433T_HUMAN (1-238): 1e-107: 312: 71.85		MEFV_HUMAN (12-473): 8.74e-112: 349: 22.93
+	Hs
		691404 1433T_HUMAN (1-238): 1e-107: 312: 71.85		TRIM4_HUMAN (2-474): 7.25e-110: 336: 22.24
+	Hs
		971457 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		TRI26_HUMAN (4-363): 5.14e-32: 130: 28.61