Interactor 1: P5CR1 (P32322)
Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2)
Gene: PYCR1
Interactor 2: SIR3 (Q9NTG7)
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 2.3.1.286) (NAD-dependent protein delactylase sirtuin-3) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3)
Gene: SIRT3
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 0.60 | 0.578 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31108370 |
| Identification Methods | affinity chromatography technology, pull down, enzymatic study |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
