HitPredict

Interactor 1: GBP1 (P32455)
Guanylate-binding protein 1 (EC 3.6.1.-) (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (HuGBP-1) (hGBP1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1)
Gene: GBP1

Interactor 2: GBP1 (P32455)
Guanylate-binding protein 1 (EC 3.6.1.-) (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (HuGBP-1) (hGBP1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1)
Gene: GBP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 16511497, 21151871, 22059445, 22607347
Identification Methods x-ray crystallography, molecular sieving, anti tag coimmunoprecipitation, bimolecular fluorescence complementation, two hybrid, cross-linking study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GBP~GBP, GBP~GBP_C, GBP_C~GBP_C
Common GO terms GO:0000139 - Golgi membrane
GO:0001530 - lipopolysaccharide binding
GO:0003779 - actin binding
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
and 36 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 592
Hs

1 592
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Service provided by Combinatics, Japan

Last updated: 11Aug2025