Protein: GBP6
Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6)

Gene: GBP6
Organism: Homo sapiens
Interactions: 20
UniProt ID: Q6ZN66

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0006955 - immune response
GO:0031410 - cytoplasmic vesicle
GO:0042742 - defense response to bacterium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1252729

GBP7
Guanylate-binding protein 7

2

14

High-throughput

0.802

High

1252728

FRMD1
FERM domain-containing protein 1

2

1

High-throughput

0.574

High

1154381

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.513

High

1143169

PLEC
Plectin

1

0

High-throughput

0.493

High

1252730

FNDC5
Fibronectin type III domain-containing protein 5

1

3

High-throughput

0.489

High

595480

H15
Histone H1.5

1

4

High-throughput

0.470

High

596181

H12
Histone H1.2

1

4

High-throughput

0.470

High

1037227

H11
Histone H1.1

1

4

High-throughput

0.470

High

242058

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.437

High

290328

KS6A4
Ribosomal protein S6 kinase alpha-4

1

3

High-throughput

0.437

High

414068

P53
Cellular tumor antigen p53

1

1

High-throughput

0.437

High

908131

KS6A3
Ribosomal protein S6 kinase alpha-3

1

3

High-throughput

0.437

High

1148350

KS6A1
Ribosomal protein S6 kinase alpha-1

1

3

High-throughput

0.437

High

1044355

HSF2
Heat shock factor protein 2

1

0

High-throughput

0.279

Low

1252727

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.279

Low

1252732

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.279

Low

1252733

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

1

0

High-throughput

0.279

Low

1062519

DHX9
ATP-dependent RNA helicase A

1

0

High-throughput

0.269

Low

1252726

RLGPB
Ral GTPase-activating protein subunit beta

1

0

High-throughput

0.249

Low

1252731

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025