Interactor 1: RPB1 (P36594)
DNA-directed RNA polymerase II subunit rpb1 (RNA polymerase II subunit 1) (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit)
Gene: RPB1

Interactor 2: RPAB1 (Q09191)
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (RPC24B)
Gene: rpb5

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.954

The method score is based on:

Property Details
Experiments 9738888, 9077438, 9642054, 10648788, 9325316, 15743411, 14534314
Identification Methods two hybrid, pull down, far western blotting, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~RNA_pol_Rpb5_C, RNA_pol_Rpb1_1~RNA_pol_Rpb5_N, RNA_pol_Rpb1_5~RNA_pol_Rpb5_C, RNA_pol_Rpb1_5~RNA_pol_Rpb5_N
Common GO terms GO:0001055 - RNA polymerase II activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1752
Sp

1 210
+ At
+ Sc
+ Hs
+ Sc
+ Hv
+ Hs
+ Sc
+ At
+ At
+ At
+ At
+ Bt
+ Hs
+ Hv

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Last updated: 15 Jul 2024