Protein: GBP2
Guanylate-binding protein 2 (EC 3.6.5.-) (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2) (Interferon-induced guanylate-binding protein 2)

Gene: GBP2
Organism: Homo sapiens
Interactions: 45
UniProt ID: P32456

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0002218 - activation of innate immune response
GO:0003924 - GTPase activity
GO:0004866 - endopeptidase inhibitor activity
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

736878

GBP1
Guanylate-binding protein 1

3

14

Small-scale

0.867

High

736928

GBP3
Guanylate-binding protein 3

3

14

Small-scale

0.867

High

736923

GBP7
Guanylate-binding protein 7

2

14

High-throughput

0.811

High

736903

GBP2
Guanylate-binding protein 2

1

14

Small-scale

0.683

High

736925

GBP5
Guanylate-binding protein 5

1

14

Small-scale

0.665

High

736926

GBP4
Guanylate-binding protein 4

1

14

Small-scale

0.665

High

461194

HS90A
Heat shock protein HSP 90-alpha

2

2

High-throughput

0.628

High

468116

HS90B
Heat shock protein HSP 90-beta

2

2

High-throughput

0.628

High

736904

ADDA
Alpha-adducin

2

3

High-throughput

0.628

High

736929

ADDG
Gamma-adducin

2

3

High-throughput

0.628

High

736921

HS905
Putative heat shock protein HSP 90-alpha A5

2

3

High-throughput

0.552

High

736909

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.541

High

736924

TFG
Protein TFG

1

2

High-throughput

0.541

High

736927

BTBD2
BTB/POZ domain-containing protein 2

1

1

High-throughput

0.541

High

736911

PCBP3
Poly(rC)-binding protein 3

1

1

High-throughput

0.536

High

736930

SSUH2
Protein SSUH2 homolog

1

2

High-throughput

0.536

High

639585

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.518

High

736907

SPS1
Selenide, water dikinase 1

1

0

High-throughput

0.518

High

736908

SPB9
Serpin B9

1

0

High-throughput

0.518

High

736915

PP1R8
Nuclear inhibitor of protein phosphatase 1

1

0

High-throughput

0.518

High

736918

PA1B3
Platelet-activating factor acetylhydrolase IB subunit alpha1

1

0

High-throughput

0.518

High

736931

KLH20
Kelch-like protein 20

1

0

High-throughput

0.518

High

736932

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

0

High-throughput

0.518

High

599548

STMN1
Stathmin

1

0

High-throughput

0.513

High

736914

HBA
Hemoglobin subunit alpha

1

0

High-throughput

0.513

High

736916

STK3
Serine/threonine-protein kinase 3

1

1

High-throughput

0.508

High

736917

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

1

High-throughput

0.508

High

736919

KS6A1
Ribosomal protein S6 kinase alpha-1

1

3

High-throughput

0.508

High

239355

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

0

High-throughput

0.486

High

627928

ANXA7
Annexin A7

1

0

High-throughput

0.486

High

665237

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.486

High

736906

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.486

High

736910

BID
BH3-interacting domain death agonist

1

0

High-throughput

0.486

High

736913

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.486

High

736933

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

413282

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

521558

H14
Histone H1.4

1

4

High-throughput

0.479

High

685423

U2AF2
Splicing factor U2AF 65 kDa subunit

1

2

High-throughput

0.479

High

736922

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

612892

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

736905

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

736934

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

736920

H90B3
Putative heat shock protein HSP 90-beta-3

1

2

High-throughput

0.445

High

736912

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025