HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26186194, 27880917, 28514442, 28330616, 30344098, 33961781, 24366813
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~PP1_bind, PP1_bind~STPPase_N
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0007049 - cell cycle
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 323
Hs

1 3256
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024