HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21566083
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0016607 - nuclear speck GO:0042752 - regulation of circadian rhythm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 471
+	Hs
		905913 PP1A_HUMAN (1-323): 0: 579: 90.66		NONO_HUMAN (1-471): 1.15e-97: 303: 100.00
+	Hs
		906467 PP1B_HUMAN (1-322): 0: 560: 86.89		NONO_HUMAN (1-471): 1.15e-97: 303: 100.00
+	Hs
		737785 PP1G_HUMAN (1-323): 0: 603: 100.00		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		737946 PP1G_HUMAN (1-323): 0: 603: 100.00		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		516386 PP1G_HUMAN (1-323): 0: 603: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		905870 PP1A_HUMAN (1-323): 0: 579: 90.66		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		906046 PP1A_HUMAN (1-323): 0: 579: 90.66		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		516441 PP1A_HUMAN (1-323): 0: 579: 90.66		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Sp
		532280 PP11_SCHPO (7-322): 0: 555: 82.92		PABP_SCHPO (2-471): 9.26e-65: 222: 14.98
+	Hs
		613400 PP1A_HUMAN (1-323): 0: 579: 90.66		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Zm
		6224 B4FJL0_MAIZE (4-314): 0: 550: 75.24		A0A1D6E6L1_MAIZE (57-469): 8.21e-61: 211: 14.43
+	Hs
		905922 PP1A_HUMAN (1-323): 0: 579: 90.66		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		906472 PP1B_HUMAN (1-322): 0: 560: 86.89		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		516454 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89