HitPredict

Interactor 1: ZEB1 (P37275)
Zinc finger E-box-binding homeobox 1 (NIL-2-A zinc finger protein) (Negative regulator of IL2) (Transcription factor 8) (TCF-8)
Gene: ZEB1

Interactor 2: ZN516 (Q92618)
Zinc finger protein 516
Gene: ZNF516

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34462429
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	zf-C2H2~zf-C2H2
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1124 Hs			1 1163
+	Hs
		974627 MECOM_HUMAN (58-1121): 4.17e-93: 326: 17.27		ZN516_HUMAN (1-1163): 0: 1179: 100.00
+	Hs
		231250 ZEB2_HUMAN (116-192): 4.11e-11: 69.5: 9.09		ZN516_HUMAN (1-1163): 0: 1179: 100.00
+	Hs
		1149640 Z324B_HUMAN (904-978): 1.79e-10: 67: 37.33		ZN624_HUMAN (468-1162): 2.64e-166: 516: 8.81
+	Hs
		1055930 ZN112_HUMAN (2-869): 3.17e-120: 394: 8.96		ZN235_HUMAN (176-357): 3.2e-09: 63.2: 27.18
+	Hs
		563267 ZN708_HUMAN (59-356): 8.57e-82: 279: 14.16		ZN543_HUMAN (276-551): 8.01e-32: 134: 15.90
+	Hs
		1239558 ZNF71_HUMAN (809-1078): 5.6e-58: 210: 21.28		ZFP62_HUMAN (848-1162): 2.64e-50: 195: 8.59
+	Hs
		1305550 ZNF71_HUMAN (809-1078): 5.6e-58: 210: 21.28		ZN184_HUMAN (909-1162): 2.2e-43: 172: 12.84
+	Hs
		1149643 Z324B_HUMAN (904-978): 1.79e-10: 67: 37.33		ZN107_HUMAN (679-1162): 1.65e-90: 310: 8.84
+	Hs
		264766 ZN479_HUMAN (54-340): 3.68e-77: 265: 16.72		ZN254_HUMAN (3-89): 3.67e-21: 101: 27.59
+	Hs
		64162 ZN430_HUMAN (753-949): 2.65e-27: 120: 13.97		ZN726_HUMAN (119-541): 2.2e-57: 211: 15.62
+	Hs
		64156 ZN716_HUMAN (278-397): 3.33e-27: 119: 12.69		ZN726_HUMAN (119-541): 2.2e-57: 211: 15.62
+	Hs
		565101 ZNF71_HUMAN (809-1078): 5.6e-58: 210: 21.28		ZNF7_HUMAN (36-373): 3.92e-19: 95.1: 25.41
+	Hs
		1198596 ZN554_HUMAN (860-976): 1.02e-36: 148: 29.06		ZN808_HUMAN (916-1162): 2.93e-36: 150: 12.40
+	Hs
		477792 Z324B_HUMAN (904-978): 1.79e-10: 67: 37.33		ZN888_HUMAN (814-1161): 2.08e-46: 180: 8.26
+	Hs
		1149641 Z324B_HUMAN (904-978): 1.79e-10: 67: 37.33		ZN629_HUMAN (892-1161): 6.9e-44: 174: 11.72
+	Hs
		1149620 Z324B_HUMAN (904-978): 1.79e-10: 67: 37.33		ZN184_HUMAN (909-1162): 2.2e-43: 172: 12.84
+	Hs
		1162544 ZN773_HUMAN (221-286): 9.9e-10: 64.3: 48.49		ZN629_HUMAN (892-1161): 6.9e-44: 174: 11.72
+	Hs
		563492 ZNF22_HUMAN (904-959): 3.88e-09: 60.1: 44.64		ZN808_HUMAN (916-1162): 2.93e-36: 150: 12.40
+	Hs
		265813 Z324A_HUMAN (172-286): 3.52e-09: 62.8: 31.06		ZN543_HUMAN (276-551): 8.01e-32: 134: 15.90