HitPredict

Interactor 1: BRR2 (P32639)
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)
Gene: BRR2

Interactor 2: IST3 (P40565)
U2 snRNP component IST3 (Increased sodium tolerance protein 3) (U2 snRNP protein SNU17)
Gene: IST3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37968396, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0000974 - Prp19 complex GO:0005634 - nucleus GO:0005681 - spliceosomal complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2163 Sc			1 148
+	Hs
		289536 U520_HUMAN (16-2163): 0: 1598: 38.93		RBM39_HUMAN (10-114): 1.16e-20: 88.7: 23.81
+	Hs
		550360 ASCC3_HUMAN (58-2162): 0: 1386: 30.92		PABP1_HUMAN (2-144): 1.21e-25: 102: 13.33
+	Hs
		1127053 DDX17_HUMAN (1345-1753): 1.48e-96: 331: 11.35		RBM39_HUMAN (10-114): 1.16e-20: 88.7: 23.81
+	Hs
		1414629 DDX23_HUMAN (1275-1768): 5.4e-82: 291: 13.30		RBMX2_HUMAN (1-138): 3.45e-36: 128: 47.83
+	Mm
		915297 DDX17_MOUSE (1345-1753): 2e-97: 331: 11.35		TIA1_MOUSE (4-121): 1.66e-17: 79.5: 13.97
+	Hs
		608597 DDX5_HUMAN (1344-1752): 1.09e-92: 316: 11.35		RBM39_HUMAN (10-114): 1.16e-20: 88.7: 23.81
+	Mm
		1000097 DDX5_MOUSE (1344-1752): 5.49e-93: 317: 11.35		TIAR_MOUSE (4-141): 8.97e-18: 80.2: 12.82
+	Mm
		915325 Q8BTS0_MOUSE (1344-1752): 1.43e-92: 316: 11.35		TIA1_MOUSE (4-121): 1.66e-17: 79.5: 13.97
+	Hs
		1127126 DDX23_HUMAN (1275-1768): 5.4e-82: 291: 13.30		RBM39_HUMAN (10-114): 1.16e-20: 88.7: 23.81
+	Hs
		838718 MTREX_HUMAN (355-1000): 3.38e-76: 278: 17.83		RBM39_HUMAN (10-114): 1.16e-20: 88.7: 23.81
+	Hs
		1414614 DDX23_HUMAN (1275-1768): 5.4e-82: 291: 13.30		PUF60_HUMAN (33-111): 5.39e-10: 58.2: 31.65
+	Hs
		1128160 DHX8_HUMAN (1353-1741): 3.69e-48: 191: 11.03		RBMX2_HUMAN (1-138): 3.45e-36: 128: 47.83
+	Zm
		18350 A0A1D6H4I5_MAIZE (1352-1795): 2.2e-52: 205: 11.88		A0A1D6IK73_MAIZE (25-134): 1.33e-31: 114: 25.46
+	Hs
		1365869 PRP16_HUMAN (1247-1876): 2.03e-47: 189: 9.65		RBMX2_HUMAN (1-138): 3.45e-36: 128: 47.83
+	Hs
		1126878 DHX8_HUMAN (1353-1741): 3.69e-48: 191: 11.03		RBM39_HUMAN (10-114): 1.16e-20: 88.7: 23.81
+	Hs
		1127048 PRP16_HUMAN (1247-1876): 2.03e-47: 189: 9.65		RBM39_HUMAN (10-114): 1.16e-20: 88.7: 23.81