HitPredict

Interactor 1: MAK5 (P38112)
ATP-dependent RNA helicase MAK5 (EC 3.6.4.13) (Maintenance of killer protein 5)
Gene: MAK5

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	23332755, 19536198
Identification Methods	biochemical, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0016887 - ATP hydrolysis activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 773 Sc			1 613
+	Sc
		511021 MAK5_YEAST (1-773): 3.79e-163: 493: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		624216 DBP1_YEAST (31-616): 1.92e-122: 382: 22.46		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		624104 DBP2_YEAST (62-611): 3.49e-122: 379: 21.62		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510336 DBP2_YEAST (62-611): 3.49e-122: 379: 21.62		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		415991 DED1_YEAST (146-611): 4.99e-117: 367: 25.31		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		415872 DED1_YEAST (146-611): 4.99e-117: 367: 25.31		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		504292 DDX46_HUMAN (41-702): 7.58e-144: 450: 23.17		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		133856 DDX3X_HUMAN (28-618): 9.99e-129: 400: 20.92		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		504506 DDX17_HUMAN (107-668): 5.25e-127: 397: 22.20		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		503397 DDX5_HUMAN (107-672): 6.11e-125: 389: 22.16		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Sc
		769321 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510727 DRS1_YEAST (174-666): 9.19e-41: 162: 29.06		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		512525 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		753142 DBP8_YEAST (178-619): 1.57e-39: 153: 29.33		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		511184 DBP8_YEAST (178-619): 1.57e-39: 153: 29.33		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		504721 DDX24_HUMAN (242-734): 2.14e-67: 241: 33.13		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		504735 DDX47_HUMAN (182-577): 1.57e-44: 168: 29.72		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		504840 DDX18_HUMAN (70-598): 3.25e-38: 153: 29.16		HSP7C_HUMAN (5-612): 0: 897: 60.00