Protein: RIR3
Ribonucleoside-diphosphate reductase large chain 2 (EC 1.17.4.1) (Ribonucleotide reductase DNA damage-inducible regulatory subunit 2) (Ribonucleotide reductase R1 subunit 2) (Ribonucleotide reductase large subunit 2)

Gene: RIR3, RNR3
Organism: Saccharomyces cerevisiae S288C
Interactions: 56
UniProt ID: P21672

Gene Ontology (top 5):
GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005971 - ribonucleoside-diphosphate reductase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

599159

RIR1
Ribonucleoside-diphosphate reductase large chain 1

4

9

Small-scale

0.890

High

599978

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

13

High-throughput

0.618

High

599958

MAS5
Mitochondrial protein import protein MAS5

2

3

High-throughput

0.584

High

599976

MPG1
Mannose-1-phosphate guanyltransferase

2

0

High-throughput

0.569

High

489666

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.536

High

516188

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.536

High

599961

ARP2
Actin-related protein 2

1

1

High-throughput

0.536

High

599960

TF2B
Transcription initiation factor IIB

2

1

High-throughput

0.526

High

599963

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.513

High

599973

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.513

High

599982

YNN4
Uncharacterized protein YNL134C

1

0

High-throughput

0.513

High

599986

CCE1
Cruciform cutting endonuclease 1, mitochondrial

1

0

High-throughput

0.513

High

599990

SML1
Ribonucleotide reductase inhibitor protein SML1

1

1

Small-scale

0.508

High

454179

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.500

High

554552

HSP26
Heat shock protein 26

1

2

High-throughput

0.500

High

587928

HSP60
Heat shock protein 60, mitochondrial

1

2

High-throughput

0.500

High

599956

SCJ1
DnaJ-related protein SCJ1

1

3

High-throughput

0.500

High

599993

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.500

High

355344

H2B1
Histone H2B.1

1

3

High-throughput

0.489

High

599968

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

0

High-throughput

0.486

High

599984

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

1

High-throughput

0.481

High

360736

TBB
Tubulin beta chain

1

0

High-throughput

0.479

High

367740

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.479

High

423755

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.479

High

452955

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.479

High

599965

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.479

High

599971

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.479

High

599983

ACT
Actin

1

0

High-throughput

0.479

High

599985

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.479

High

420043

TYSY
Thymidylate synthase

1

1

High-throughput

0.479

High

543194

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

599959

RFA2
Replication factor A protein 2

1

1

High-throughput

0.479

High

599967

SRX1
Sulfiredoxin

1

0

High-throughput

0.458

High

599977

RFX1
RFX-like DNA-binding protein RFX1

1

0

High-throughput

0.458

High

599979

ORC5
Origin recognition complex subunit 5

1

0

High-throughput

0.458

High

599980

MTM1
Mitochondrial carrier protein MTM1

1

0

High-throughput

0.458

High

599981

SPC98
Spindle pole body component SPC98

1

0

High-throughput

0.458

High

599988

HLR1
Protein HLR1

1

0

High-throughput

0.458

High

599989

KRE28
Spindle pole body component KRE28

1

0

High-throughput

0.458

High

599992

S2538
Mitochondrial glycine transporter

1

0

High-throughput

0.458

High

599994

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

599975

BNI1
Protein BNI1

1

1

High-throughput

0.457

High

510257

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

599966

LHS1
Heat shock protein 70 homolog LHS1

1

4

High-throughput

0.445

High

599970

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

599991

BRE1
E3 ubiquitin-protein ligase BRE1

1

1

High-throughput

0.437

High

599957

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.279

Low

599962

RPN12
26S proteasome regulatory subunit RPN12

1

0

High-throughput

0.279

Low

599987

RPN9
26S proteasome regulatory subunit RPN9

1

0

High-throughput

0.279

Low

378284

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

549646

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

599955

CLH
Clathrin heavy chain

1

0

High-throughput

0.261

Low

599964

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

High-throughput

0.249

Low

599972

MSL1
U2 small nuclear ribonucleoprotein B''

1

0

High-throughput

0.249

Low

599974

LST8
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.249

Low

599969

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024