Interactor 1: PRS6B (P33298)
26S proteasome regulatory subunit 6B homolog (Protein YNT1) (Tat-binding homolog 2)
Gene: RPT3

Interactor 2: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 10688190, 11595789, 24013205, 11805837, 26301997, 9724628, 36621624, 37968396, 31848235, 22307589
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, pull down, biochemical, cross-linking study, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB_C, Prot_ATP_ID_OB_C~Prot_ATP_ID_OB_C
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0016887 - ATP hydrolysis activity
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 428
Sc

1 437
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Dm
+ At
+ Dm
+ Dm
+ Dm
+ At
+ At
+ Dm
+ Sc
+ Sc
+ Dm
+ Sc

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Last updated: 11Aug2025