HitPredict

Interactor 1: VATA (P38606)
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha)
Gene: ATP6V1A

Interactor 2: VATD (Q9Y5K8)
V-type proton ATPase subunit D (V-ATPase subunit D) (V-ATPase 28 kDa accessory protein) (Vacuolar proton pump subunit D)
Gene: ATP6V1D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 35271311, 33961781, 21674799
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-synt_D~ATP-synt_ab
Common GO terms GO:0000139 - Golgi membrane
GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005654 - nucleoplasm
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
and 17 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 617
Hs

1 247
+ Mm
+ Dm
+ Dm
+ Tt
+ Sc
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024