HitPredict

Interactor 1: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 679 Hs			1 665
+	Hs
		504539 HSP7C_HUMAN (51-653): 0: 883: 50.16		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		505017 HSP7C_HUMAN (51-653): 0: 883: 50.16		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		503853 HSP7C_HUMAN (51-653): 0: 883: 50.16		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		713938 HS71L_HUMAN (49-673): 0: 883: 47.59		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		751568 GRP75_HUMAN (1-679): 0: 873: 100.00		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		502411 BIP_HUMAN (53-677): 0: 566: 50.55		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Ce
		450542 HSP1_CAEEL (54-653): 0: 870: 50.81		Q9U2T9_CAEEL (142-349): 4.59e-14: 78.1: 18.48
+	Hs
		501645 BIP_HUMAN (53-677): 0: 566: 50.55		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		501953 BIP_HUMAN (53-677): 0: 566: 50.55		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Ce
		647814 HSP7C_CAEEL (53-677): 0: 567: 49.45		Q9U2T9_CAEEL (142-349): 4.59e-14: 78.1: 18.48