HitPredict

Interactor 1: GCYA2 (P33402)
Guanylate cyclase soluble subunit alpha-2 (GCS-alpha-2) (EC 4.6.1.2)
Gene: GUCY1A2

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	11572861, 30126976
Identification Methods	affinity chromatography technology, p8 filamentous phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 904
+	Rn
		1224266 GCYA2_RAT (1-732): 0: 907: 90.98		DLG1_RAT (1-904): 0: 679: 92.65
+	Rn
		1224330 GCYA2_RAT (1-732): 0: 907: 90.98		DLG3_RAT (99-904): 0: 575: 65.42
+	Rn
		723906 GCYA2_RAT (1-732): 0: 907: 90.98		DLG4_RAT (175-904): 0: 549: 71.18
+	Hs
		752045 GCYA2_HUMAN (1-732): 0: 865: 100.00		DLG3_HUMAN (137-904): 0: 569: 66.11
+	Hs
		752038 GCYA2_HUMAN (1-732): 0: 865: 100.00		DLG4_HUMAN (175-904): 0: 550: 71.31
+	Rn
		633436 GCYB1_RAT (112-705): 0: 646: 33.76		DLG4_RAT (175-904): 0: 549: 71.18
+	Rn
		1224611 GCYA2_RAT (1-732): 0: 907: 90.98		DLG2_RAT (392-627): 1.23e-17: 90.3: 21.90
+	Hs
		752044 GCYA2_HUMAN (1-732): 0: 865: 100.00		DLG2_HUMAN (392-627): 2.73e-17: 89.1: 21.90