HitPredict

Interactor 1: ORC6 (P38826)
Origin recognition complex subunit 6 (ACS-associated protein 1) (Origin recognition complex 50 kDa subunit)
Gene: ORC6

Interactor 2: ORC4 (P54791)
Origin recognition complex subunit 4 (Origin recognition complex 56 kDa subunit)
Gene: ORC4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.727

The method score is based on:

Property	Details
Experiments	9001208, 17880717, 35217664, 16554755, 16429126, 37968396
Identification Methods	coimmunoprecipitation, affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003688 - DNA replication origin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005656 - nuclear pre-replicative complex GO:0005664 - nuclear origin of replication recognition complex and 4 others more... GO:0006267 - pre-replicative complex assembly involved in nuclear cell cycle DNA replication GO:0006270 - DNA replication initiation GO:0030466 - silent mating-type cassette heterochromatin formation GO:0031261 - DNA replication preinitiation complex
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	435
Sc

1	529

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024