HitPredict

Interactor 1: DHH1 (P39517)
ATP-dependent RNA helicase DHH1 (EC 3.6.4.13) (DExD/H-box helicase 1)
Gene: DHH1

Interactor 2: DCP2 (P53550)
m7GpppN-mRNA hydrolase (EC 3.6.1.62) (Protein PSU1) (mRNA-decapping enzyme subunit 2)
Gene: DCP2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.716

The method score is based on:

Property Details
Experiments 26392412, 17984320, 18467557, 20832728, 24569876
Identification Methods affinity chromatography technology, two hybrid, pull down, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0003682 - chromatin binding
GO:0003729 - mRNA binding
GO:0005737 - cytoplasm
and 3 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 506
Sc

1 970
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024