HitPredict

Interactor 1: PSA2 (P40301)
Proteasome subunit alpha type-2 (PROS-Dm25) (Proteasome 25 kDa subunit)
Gene: Prosalpha2

Interactor 2: Q9VK14 (Q9VK14)
Proteasome subunit alpha type
Gene: Prosalpha6T

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms	GO:0005829 - cytosol GO:0019773 - proteasome core complex, alpha-subunit complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 234 Dm			1 289
+	Hs
		637325 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19
+	Ss
		94704 F2Z5K2_PIG (1-233): 1.45e-98: 288: 31.38		F2Z5L7_PIG (1-262): 7.51e-107: 312: 50.19
+	Sp
		145200 PSA5_SCHPO (1-231): 3.4e-100: 293: 32.77		PSA6_SCHPO (1-255): 1.06e-101: 299: 44.53
+	Hs
		637316 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSA1_HUMAN (1-262): 7.51e-107: 312: 50.19
+	Ce
		218159 PSA2_CAEEL (4-233): 3.6e-99: 289: 60.35		PSA1_CAEEL (1-236): 2.32e-101: 298: 47.68
+	Hs
		637631 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41
+	Hs
		637624 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSA2_HUMAN (1-236): 2.12e-101: 297: 29.41
+	Dm
		522499 PSA5_DROME (1-233): 1.55e-97: 286: 30.71		PSA1_DROME (1-237): 1.09e-97: 290: 63.90
+	Hs
		156230 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSA7_HUMAN (6-233): 9.24e-96: 284: 35.93
+	Dm
		522481 PSA2_DROME (1-234): 2.1e-95: 280: 100.00		PSA1_DROME (1-237): 1.09e-97: 290: 63.90
+	Hs
		656149 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSA5_HUMAN (1-235): 9.39e-95: 281: 29.34
+	Hs
		638067 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSA4_HUMAN (1-232): 6.37e-94: 279: 28.87
+	Hs
		656189 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSA6_HUMAN (1-239): 4.74e-94: 279: 28.34
+	Hs
		656276 PSA5_HUMAN (1-233): 1.45e-98: 288: 31.38		PSMA8_HUMAN (4-233): 8.8e-94: 279: 35.57
+	Hs
		156224 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSA7_HUMAN (6-233): 9.24e-96: 284: 35.93
+	Hs
		637626 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSA4_HUMAN (1-232): 6.37e-94: 279: 28.87
+	Hs
		637663 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSA6_HUMAN (1-239): 4.74e-94: 279: 28.34
+	Hs
		637719 PSA2_HUMAN (1-233): 1.3e-95: 280: 78.11		PSMA8_HUMAN (4-233): 8.8e-94: 279: 35.57
+	Dm
		771303 PSA2_DROME (1-234): 2.1e-95: 280: 100.00		PSA5_DROME (1-236): 3.53e-94: 279: 28.57