HitPredict

Interactor 1: SEC24 (P40482)
Protein transport protein SEC24 (Abnormal nuclear morphology 1)
Gene: SEC24

Interactor 2: SEC13 (Q04491)
Protein transport protein SEC13
Gene: SEC13

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	23904270, 16429126, 18046405
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0030127 - COPII vesicle coat GO:0070863 - positive regulation of protein exit from endoplasmic reticulum GO:1902953 - positive regulation of ER to Golgi vesicle-mediated transport
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 926 Sc			1 297
+	Sc
		866702 SFB2_YEAST (126-926): 0: 732: 59.22		SEC13_YEAST (1-297): 1.93e-83: 254: 100.00
+	Dm
		1279323 Q9VNF8_DROME (174-922): 0: 685: 14.55		EBI_DROME (1-285): 5.78e-62: 209: 20.35
+	Dm
		52831 A1Z813_DROME (1-925): 0: 646: 26.87		EBI_DROME (1-285): 5.78e-62: 209: 20.35
+	Sc
		546787 SEC23_YEAST (174-903): 0: 588: 14.77		SEC13_YEAST (1-297): 1.93e-83: 254: 100.00
+	Hs
		315675 SC24B_HUMAN (70-926): 0: 738: 30.44		SEC13_HUMAN (3-104): 2.32e-09: 59.3: 25.46
+	Hs
		315535 SC24A_HUMAN (14-926): 0: 715: 28.90		SEC13_HUMAN (3-104): 2.32e-09: 59.3: 25.46
+	Hs
		878185 SC23B_HUMAN (174-922): 0: 671: 13.29		SEC13_HUMAN (3-104): 2.32e-09: 59.3: 25.46
+	Hs
		878184 SC23A_HUMAN (174-922): 0: 668: 13.20		SEC13_HUMAN (3-104): 2.32e-09: 59.3: 25.46
+	Hs
		867085 SC24C_HUMAN (2-307): 1.33e-14: 80.6: 11.22		SEC13_HUMAN (3-104): 2.32e-09: 59.3: 25.46
+	Hs
		297852 SC24D_HUMAN (1-322): 4.5e-12: 72.5: 9.35		SEC13_HUMAN (3-104): 2.32e-09: 59.3: 25.46