HitPredict

Interactor 1: PSMD9 (P40555)
Probable 26S proteasome regulatory subunit p27 (Proteasome non-ATPase subunit 2)
Gene: NAS2

Interactor 2: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.966

Property	Details
Experiments	24685148, 30530678, 33862083, 19446322, 19446323, 15687504, 36621624, 23900548
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	AAA_lid_3~Nas2_N
Common GO terms	GO:0005634 - nucleus GO:0070682 - proteasome regulatory particle assembly
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 220 Sc			1 437
+	Hs
		122171 PSMD9_HUMAN (31-220): 1.58e-88: 261: 37.00		PRS8_HUMAN (43-437): 1.18e-135: 397: 41.29
+	Hs
		122178 PSMD9_HUMAN (31-220): 1.58e-88: 261: 37.00		PRS10_HUMAN (51-437): 1.51e-129: 381: 67.70
+	Dm
		820512 PSMD9_DROME (30-219): 6.19e-70: 214: 27.32		PRS4_DROME (27-428): 6.75e-136: 399: 37.99
+	Sc
		775495 PSMD9_YEAST (1-220): 2.39e-101: 294: 100.00		PRS8_YEAST (73-437): 2.68e-99: 304: 44.89
+	Dm
		1365663 PSMD9_DROME (30-219): 6.19e-70: 214: 27.32		Q9W414_DROME (50-437): 3.69e-127: 375: 68.81
+	Dm
		1249398 PSMD9_DROME (30-219): 6.19e-70: 214: 27.32		Q8SZ19_DROME (50-437): 5.89e-127: 374: 68.56
+	Sc
		703913 PSMD9_YEAST (1-220): 2.39e-101: 294: 100.00		PRS7_YEAST (116-436): 9.22e-93: 289: 46.89
+	Dm
		1365658 PSMD9_DROME (30-219): 6.19e-70: 214: 27.32		Q9VTQ9_DROME (41-437): 4.34e-123: 364: 64.23
+	Hs
		122158 PSMD9_HUMAN (31-220): 1.58e-88: 261: 37.00		PRS6B_HUMAN (1-123): 4.23e-09: 60.2: 8.03
+	Dm
		186146 PSMD9_DROME (30-219): 6.19e-70: 214: 27.32		PRS8_DROME (1-147): 2.61e-09: 60.9: 9.32