HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: DD19A (Q9NUU7)
ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DDX19-like protein) (DEAD box protein 19A)
Gene: DDX19A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DEAD~NUP214
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2090 Hs			1 478
+	Hs
		775617 NU214_HUMAN (1-2090): 0: 715: 100.00		DD19B_HUMAN (1-478): 4.83e-137: 404: 96.03
+	Hs
		615339 SON_HUMAN (277-1824): 2.99e-54: 213: 9.94		IF4A3_HUMAN (72-473): 5.66e-129: 382: 34.57
+	At
		100036 NP214_ARATH (29-1826): 6.27e-61: 234: 14.60		RH38_ARATH (49-477): 1.35e-89: 283: 38.18
+	Hs
		141719 PRC2C_HUMAN (580-2063): 3.97e-32: 140: 10.76		DDX3X_HUMAN (11-475): 3.9e-120: 367: 24.75
+	Hs
		807419 MDC1_HUMAN (422-1387): 2.17e-26: 121: 9.96		IF4A3_HUMAN (72-473): 5.66e-129: 382: 34.57
+	Hs
		1369354 CIC_HUMAN (881-1968): 1.92e-11: 72.2: 8.39		DDX17_HUMAN (16-473): 2.84e-123: 377: 24.52
+	Hs
		608708 CIC_HUMAN (881-1968): 1.92e-11: 72.2: 8.39		DDX5_HUMAN (33-474): 2.44e-123: 374: 24.28
+	Hs
		141627 CIC_HUMAN (881-1968): 1.92e-11: 72.2: 8.39		DDX3X_HUMAN (11-475): 3.9e-120: 367: 24.75
+	Hs
		1124324 PRC2C_HUMAN (580-2063): 3.97e-32: 140: 10.76		IF4A2_HUMAN (90-473): 9.9e-75: 242: 40.00
+	Hs
		954040 PRC2C_HUMAN (580-2063): 3.97e-32: 140: 10.76		IF4A1_HUMAN (90-473): 2.34e-73: 238: 39.95
+	Hs
		953969 CIC_HUMAN (881-1968): 1.92e-11: 72.2: 8.39		IF4A1_HUMAN (90-473): 2.34e-73: 238: 39.95