HitPredict

Interactor 1: WNT4 (P40589)
Protein Wnt-4 (dWnt-4)
Gene: WNT4

Interactor 2: WLS (Q95ST2)
Protein wntless (Evenness interrupted) (Sprinter)
Gene: WLS

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22108505
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MIG-14_Wnt-bd~wnt
Common GO terms	GO:0016055 - Wnt signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 539 Dm			1 594
+	Dm
		658764 WNT2_DROME (220-539): 4.45e-118: 354: 31.30		WLS_DROME (1-594): 0: 914: 100.00
+	Mm
		568285 WNT3_MOUSE (230-539): 2.32e-154: 446: 31.90		WLS_MOUSE (1-585): 0: 790: 40.65
+	Hs
		881860 WNT3A_HUMAN (230-539): 4.39e-152: 440: 31.90		WLS_HUMAN (1-585): 0: 785: 40.82
+	Dm
		1279554 Q9VM25_DROME (240-522): 3.79e-91: 289: 26.21		WLS_DROME (1-594): 0: 914: 100.00
+	Hs
		881881 WNT4_HUMAN (227-539): 1.71e-137: 403: 32.73		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		881899 WNT7B_HUMAN (238-539): 6.01e-137: 402: 32.00		WLS_HUMAN (1-585): 0: 785: 40.82
+	Mm
		611175 WNT5A_MOUSE (233-539): 3.45e-133: 393: 30.00		WLS_MOUSE (1-585): 0: 790: 40.65
+	Hs
		451998 WNT2_HUMAN (234-539): 1.06e-134: 397: 33.95		WLS_HUMAN (1-585): 0: 785: 40.82
+	Mm
		382254 WNT1_MOUSE (245-538): 1.57e-132: 391: 31.49		WLS_MOUSE (1-585): 0: 790: 40.65
+	Hs
		1135438 WNT5B_HUMAN (233-539): 2.41e-134: 395: 30.51		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		135861 WNT7A_HUMAN (238-539): 6.95e-134: 394: 31.69		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		782089 WNT5A_HUMAN (233-539): 1.82e-133: 394: 30.00		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		158068 WNT9A_HUMAN (240-539): 1.51e-132: 391: 33.23		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		384072 WNT1_HUMAN (245-538): 2.8e-132: 391: 31.49		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		158076 WNT9B_HUMAN (226-539): 4.36e-129: 382: 35.54		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		1135451 WNT16_HUMAN (240-539): 2.07e-126: 375: 34.55		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		1135437 WNT8A_HUMAN (262-538): 1.33e-118: 355: 29.10		WLS_HUMAN (1-585): 0: 785: 40.82
+	Hs
		1135420 WNT8B_HUMAN (262-538): 5.04e-106: 323: 28.09		WLS_HUMAN (1-585): 0: 785: 40.82
+	Dm
		658776 WNT5_DROME (237-376): 6.75e-43: 165: 32.88		WLS_DROME (1-594): 0: 914: 100.00
+	Dm
		1279555 Q9VM26_DROME (251-343): 2.97e-26: 112: 32.98		WLS_DROME (1-594): 0: 914: 100.00