Interactor 1: STAT1 (P42224)
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
Gene: STAT1

Interactor 2: INAR2 (P48551)
Interferon alpha/beta receptor 2 (IFN-R-2) (IFN-alpha binding protein) (IFN-alpha/beta receptor 2) (Interferon alpha binding protein) (Type I interferon receptor 2)
Gene: IFNAR2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.700

The method score is based on:

Property Details
Experiments 32123171, 9121453, 29997210, 11301323
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0007259 - cell surface receptor signaling pathway via JAK-STAT
GO:0035456 - response to interferon-beta
GO:0035458 - cellular response to interferon-beta
GO:0051607 - defense response to virus
GO:0060337 - type I interferon-mediated signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 750
Hs

1 515
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024