Protein: RHO1
GTP-binding protein RHO1 (EC 3.6.5.2) (Rho-type GTPase 1)

Gene: RHO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 75
UniProt ID: P06780

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0000148 - 1,3-beta-D-glucan synthase complex
GO:0000329 - fungal-type vacuole membrane
GO:0003924 - GTPase activity
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

448511

KPC1
Protein kinase C-like 1

11

20

Small-scale

0.979

High

448520

LRG1
Rho-GTPase-activating protein LRG1

5

20

Small-scale

0.916

High

448507

SAC7
GTPase-activating protein SAC7

5

20

Small-scale

0.915

High

448516

SEC3
Exocyst complex component SEC3

3

20

Small-scale

0.879

High

448555

ROM2
RHO1 GDP-GTP exchange protein 2

3

20

Small-scale

0.858

High

448574

GDIR
Rho GDP-dissociation inhibitor

3

20

Small-scale

0.848

High

448546

BNI1
Protein BNI1

3

20

Small-scale

0.843

High

448535

RGA1
Rho-type GTPase-activating protein 1

2

20

High-throughput

0.762

High

448571

BAG7
Rho-GTPase-activating protein BAG7

2

20

Small-scale

0.757

High

448534

GDS1
GTPase-GDP dissociation stimulator BEM4

5

0

Small-scale

0.684

High

448529

FKS1
1,3-beta-glucan synthase component FKS1

3

0

Small-scale

0.649

High

448552

GYP3
GTPase-activating protein GYP3

1

20

Small-scale

0.647

High

448531

KOG1
Target of rapamycin complex 1 subunit KOG1

2

14

Small-scale

0.624

High

448544

PSMD9
Probable 26S proteasome regulatory subunit p27

1

0

High-throughput

0.622

High

448568

TUS1
Rho1 guanine nucleotide exchange factor TUS1

1

20

Small-scale

0.621

High

448512

SIS1
Protein SIS1

1

3

High-throughput

0.618

High

448528

RCK2
Serine/threonine-protein kinase RCK2

1

4

High-throughput

0.618

High

448563

PKH1
Serine/threonine-protein kinase PKH1

1

20

High-throughput

0.618

High

448577

AIM44
Altered inheritance of mitochondria protein 44

2

0

Small-scale

0.597

High

448558

ZDS2
Protein ZDS2

2

13

Small-scale

0.595

High

448536

YCFI
Metal resistance protein YCF1

1

20

Small-scale

0.527

High

448554

ZDS1
Protein ZDS1

1

13

Small-scale

0.527

High

448533

SHC1
Protein SHC1

1

1

High-throughput

0.508

High

448570

CYK3
Cytokinesis protein 3

1

0

Small-scale

0.504

High

448522

ALY1
Arrestin-related trafficking adapter 6

1

4

Small-scale

0.501

High

448523

PXL1
Paxillin-like protein 1

1

3

Small-scale

0.501

High

448548

ROG3
Protein ROG3

1

16

Small-scale

0.501

High

448551

ALY2
Arrestin-related trafficking adapter 3

1

13

Small-scale

0.501

High

448557

ART5
Arrestin-related trafficking adapter 5

1

4

Small-scale

0.501

High

448559

2ABA
Protein phosphatase PP2A regulatory subunit B

1

4

Small-scale

0.501

High

448561

ROD1
Protein ROD1

1

4

Small-scale

0.501

High

448576

SMC6
Structural maintenance of chromosomes protein 6

1

5

High-throughput

0.500

High

448532

SKN7
Transcription factor SKN7

1

0

Small-scale

0.486

High

448575

LDB19
Protein LDB19

1

0

Small-scale

0.480

High

448505

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

17

Small-scale

0.479

High

448506

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

448508

GBB
Guanine nucleotide-binding protein subunit beta

1

14

Small-scale

0.479

High

448513

CDC48
Cell division control protein 48

1

11

High-throughput

0.479

High

448515

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

448517

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.479

High

448521

KES1
Oxysterol-binding protein homolog 4

1

20

Small-scale

0.479

High

448525

ATG8
Autophagy-related protein 8

1

4

High-throughput

0.479

High

448530

RPN1
26S proteasome regulatory subunit RPN1

1

4

High-throughput

0.479

High

448538

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

448539

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

12

High-throughput

0.479

High

448540

DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3

1

1

High-throughput

0.479

High

448543

SEC24
Protein transport protein SEC24

1

1

High-throughput

0.479

High

448545

ERG10
Acetyl-CoA acetyltransferase

1

5

High-throughput

0.479

High

448547

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

448556

ACS2
Acetyl-coenzyme A synthetase 2

1

12

High-throughput

0.479

High

448564

SEC13
Protein transport protein SEC13

1

4

High-throughput

0.479

High

448572

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

448519

NIP80
Protein NIP100

1

20

High-throughput

0.464

High

448541

SHO1
High osmolarity signaling protein SHO1

1

0

Small-scale

0.460

High

448503

OAT
Ornithine aminotransferase

1

0

High-throughput

0.458

High

448504

FUMH
Fumarate hydratase, mitochondrial

1

0

High-throughput

0.458

High

448510

MSB1
Morphogenesis-related protein MSB1

1

0

Small-scale

0.458

High

448527

CUE1
Coupling of ubiquitin conjugation to ER degradation protein 1

1

0

High-throughput

0.458

High

448537

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

448549

DUG1
Cys-Gly metallodipeptidase DUG1

1

0

High-throughput

0.458

High

448550

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.458

High

448553

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.458

High

448562

PEX25
Peroxisomal membrane protein PEX25

1

0

Small-scale

0.458

High

448565

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

448566

PEX30
Peroxisomal membrane protein PEX30

1

0

Small-scale

0.458

High

448560

UBC7
Ubiquitin-conjugating enzyme E2 7

1

8

High-throughput

0.457

High

448542

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

448526

YBF3
Putative uncharacterized protein YBL053W

1

0

High-throughput

0.438

High

448518

IXR1
Intrastrand cross-link recognition protein

1

11

Small-scale

0.437

High

448524

NU170
Nucleoporin NUP170

1

10

High-throughput

0.437

High

448567

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.265

Low

448509

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.249

Low

448514

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

448569

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.249

Low

448573

WTM1
Transcriptional modulator WTM1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025