Protein: CDC42
Cell division control protein 42 (EC 3.6.5.2) (Suppressor of RHO3 protein 2)

Gene: CDC42
Organism: Saccharomyces cerevisiae S288C
Interactions: 63
UniProt ID: P19073

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0000329 - fungal-type vacuole membrane
GO:0000747 - conjugation with cellular fusion
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001403 - invasive growth in response to glucose limitation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

618359

STE20
Serine/threonine-protein kinase STE20

21

20

Small-scale

0.988

High

618355

CLA4
Serine/threonine-protein kinase CLA4

12

20

Small-scale

0.978

High

542939

CDC24
Cell division control protein 24

9

20

Small-scale

0.973

High

618347

RGA1
Rho-type GTPase-activating protein 1

7

20

Small-scale

0.958

High

618367

GDIR
Rho GDP-dissociation inhibitor

5

20

Small-scale

0.925

High

618352

BNI1
Protein BNI1

5

20

Small-scale

0.919

High

618364

IQG1
Ras GTPase-activating-like protein IQG1

4

20

Small-scale

0.873

High

618349

BOI2
BEM1-interacting protein 2

3

20

Small-scale

0.863

High

568722

RSR1
Ras-related protein RSR1

3

20

Small-scale

0.861

High

618336

SEC3
Exocyst complex component SEC3

3

20

Small-scale

0.861

High

618368

SKM1
Serine/threonine-protein kinase SKM1

3

20

Small-scale

0.832

High

618334

BEM3
GTPase-activating protein BEM3

3

20

Small-scale

0.825

High

618340

BOI1
BEM1-interacting protein 1

2

16

Small-scale

0.800

High

618348

BEM2
GTPase-activating protein BEM2/IPL2

2

20

Small-scale

0.767

High

618363

GIC2
GTPase-interacting component 2

11

1

Small-scale

0.757

High

618343

GIC1
GTPase-interacting component 1

10

1

Small-scale

0.756

High

618330

BEM1
Bud emergence protein 1

8

20

Small-scale

0.753

High

618346

GDS1
GTPase-GDP dissociation stimulator BEM4

9

0

Small-scale

0.720

High

618356

GYP3
GTPase-activating protein GYP3

1

20

Small-scale

0.647

High

618365

MSB4
GTPase-activating protein MSB4

1

20

Small-scale

0.647

High

618369

AIM44
Altered inheritance of mitochondria protein 44

3

0

Small-scale

0.645

High

618337

LRG1
Rho-GTPase-activating protein LRG1

1

20

Small-scale

0.621

High

618353

RGD2
Rho-GTPase-activating protein RGD2

1

20

Small-scale

0.621

High

618362

RGA2
Rho-type GTPase-activating protein 2

1

20

Small-scale

0.621

High

618342

RCK2
Serine/threonine-protein kinase RCK2

1

5

High-throughput

0.618

High

618345

AXL2
Axial budding pattern protein 2

2

0

Small-scale

0.616

High

618326

STE50
Protein STE50

1

0

Small-scale

0.586

High

618319

EXO70
Exocyst complex component EXO70

2

2

Small-scale

0.584

High

618327

BUD3
Bud site selection protein 3

2

0

Small-scale

0.583

High

618332

ECM25
Protein ECM25

1

0

Small-scale

0.579

High

618331

MSB2
Signaling mucin MSB2

1

16

Small-scale

0.573

High

618321

FAR1
Cyclin-dependent kinase inhibitor FAR1

2

0

Small-scale

0.565

High

618324

SIS1
Protein SIS1

1

2

High-throughput

0.553

High

618322

MSB1
Morphogenesis-related protein MSB1

1

0

Small-scale

0.537

High

618351

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.536

High

618325

SCJ1
DnaJ-related protein SCJ1

1

4

High-throughput

0.514

High

618358

NUP49
Nucleoporin NUP49/NSP49

1

3

Small-scale

0.501

High

618328

CDC48
Cell division control protein 48

1

9

High-throughput

0.500

High

618361

FUS2
Nuclear fusion protein FUS2

1

0

Small-scale

0.480

High

618338

KES1
Oxysterol-binding protein homolog 4

1

20

Small-scale

0.479

High

618341

ATG8
Autophagy-related protein 8

1

2

High-throughput

0.479

High

618344

KEL1
Kelch repeat-containing protein 1

1

3

Small-scale

0.479

High

618350

SHO1
High osmolarity signaling protein SHO1

1

0

Small-scale

0.458

High

405020

LEU3
3-isopropylmalate dehydrogenase

1

3

High-throughput

0.457

High

453411

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.457

High

597028

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.457

High

618320

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.457

High

523001

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

543758

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

618335

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

2

High-throughput

0.437

High

618354

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.437

High

618333

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.407

High

358396

ADH2
Alcohol dehydrogenase 2

1

0

High-throughput

0.279

Low

618323

SAN1
Protein SAN1

1

0

High-throughput

0.279

Low

408551

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

High-throughput

0.261

Low

470021

GAL7
Galactose-1-phosphate uridylyltransferase

1

0

High-throughput

0.261

Low

470454

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.261

Low

618366

HSP42
Heat shock protein 42

1

0

High-throughput

0.261

Low

558570

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

618329

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

618339

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.249

Low

618357

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

618360

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025