HitPredict - High confidence protein-protein interactions

Interactor 1: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Interactor 2: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Interacting Pfam domains	Metallophos~Metallophos
Common GO terms	GO:0000159 - protein phosphatase type 2A complex GO:0000278 - mitotic cell cycle GO:0000775 - chromosome, centromeric region GO:0000922 - spindle pole GO:0004722 - protein serine/threonine phosphatase activity and 19 others more... GO:0005634 - nucleus GO:0005829 - cytosol GO:0006470 - protein dephosphorylation GO:0008637 - apoptotic mitochondrial changes GO:0010288 - response to lead ion GO:0010629 - negative regulation of gene expression GO:0010804 - negative regulation of tumor necrosis factor-mediated signaling pathway GO:0031113 - regulation of microtubule polymerization GO:0034976 - response to endoplasmic reticulum stress GO:0042542 - response to hydrogen peroxide GO:0043124 - negative regulation of canonical NF-kappaB signal transduction GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0044325 - transmembrane transporter binding GO:0046580 - negative regulation of Ras protein signal transduction GO:0046677 - response to antibiotic GO:0046872 - metal ion binding GO:0048156 - tau protein binding GO:0090443 - FAR/SIN/STRIPAK complex GO:1902996 - regulation of neurofibrillary tangle assembly
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1	309
Hs

1	309

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Last updated: 11Aug2025