HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: CYTSA (Q69YQ0)
Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Gene: SPECC1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30344098
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005815 - microtubule organizing center GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 1117
+	Hs
		968341 PP1B_HUMAN (1-322): 0: 560: 86.89		CYTSA_HUMAN (1-1117): 2.93e-74: 269: 100.00
+	Dm
		55696 Q8T0U6_DROME (19-323): 0: 535: 83.39		A1Z9J3_DROME (870-1115): 1.47e-70: 262: 25.10
+	Hs
		555657 PP1B_HUMAN (1-322): 0: 560: 86.89		ACTN1_HUMAN (1009-1116): 3.98e-50: 194: 42.20
+	Hs
		773721 PP1B_HUMAN (1-322): 0: 560: 86.89		ACTN2_HUMAN (1009-1115): 3.72e-48: 188: 41.67
+	Hs
		224679 PP1B_HUMAN (1-322): 0: 560: 86.89		ACTN4_HUMAN (1009-1116): 6.69e-48: 187: 41.28
+	Hs
		967771 PP1A_HUMAN (1-323): 0: 579: 90.66		SMTL2_HUMAN (663-1116): 1.33e-41: 161: 17.46
+	Hs
		563003 PP1A_HUMAN (1-323): 0: 579: 90.66		MYH6_HUMAN (6-949): 4.17e-34: 144: 10.02
+	Mm
		968079 PP1A_MOUSE (1-323): 0: 579: 90.36		MYH6_MOUSE (351-1030): 1.89e-25: 116: 9.97
+	Dm
		432178 PP1B_DROME (1-323): 0: 552: 82.48		MYSA_DROME (171-1082): 1.21e-30: 133: 10.86
+	Hs
		772648 PP1G_HUMAN (1-323): 0: 603: 100.00		MYH9_HUMAN (578-1049): 1.31e-13: 78: 12.21
+	Hs
		786650 PP1G_HUMAN (1-323): 0: 603: 100.00		CYTSB_HUMAN (121-509): 6.43e-12: 72.2: 10.28
+	Dm
		432208 Q8T0U6_DROME (19-323): 0: 535: 83.39		MYSA_DROME (171-1082): 1.21e-30: 133: 10.86
+	Dm
		873600 PP1B_DROME (1-323): 0: 552: 82.48		MYSN_DROME (306-1034): 9.36e-25: 114: 9.60
+	Hs
		772713 PP1A_HUMAN (1-323): 0: 579: 90.66		MYH9_HUMAN (578-1049): 1.31e-13: 78: 12.21
+	Hs
		772714 PP1B_HUMAN (1-322): 0: 560: 86.89		MYH9_HUMAN (578-1049): 1.31e-13: 78: 12.21
+	Hs
		773149 PP2AB_HUMAN (8-312): 1.92e-178: 497: 46.73		MYH10_HUMAN (227-1075): 8.57e-32: 137: 10.87
+	Hs
		968330 PP1B_HUMAN (1-322): 0: 560: 86.89		CYTSB_HUMAN (121-509): 6.43e-12: 72.2: 10.28
+	Hs
		772731 PP2AA_HUMAN (8-312): 5.37e-178: 496: 46.08		MYH9_HUMAN (578-1049): 1.31e-13: 78: 12.21
+	Hs
		994252 PP2AA_HUMAN (8-312): 5.37e-178: 496: 46.08		CYTSB_HUMAN (121-509): 6.43e-12: 72.2: 10.28