HitPredict

Interactor 1: GRIK2 (P42260)
Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6)
Gene: GRIK2

Interactor 2: GRIK5 (Q63273)
Glutamate receptor ionotropic, kainate 5 (GluK5) (Glutamate receptor KA-2) (KA2)
Gene: GRIK5

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 33724189, 34706237
Identification Methods x-ray crystallography, pull down
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd
Common GO terms GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission
GO:0008066 - glutamate receptor activity
GO:0008328 - ionotropic glutamate receptor complex
GO:0015277 - kainate selective glutamate receptor activity
and 21 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 908
Rn

1 979
+ Hs
+ Rn
+ Hs
+ Mm
+ Rn
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024