HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: SNCAP (Q9Y6H5)
Synphilin-1 (Sph1) (Alpha-synuclein-interacting protein)
Gene: SNCAIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.698

Property	Details
Experiments	24902662, 26186194, 28514442, 33961781
Identification Methods	two hybrid, far western blotting, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 919
+	Hs
		968058 PP1A_HUMAN (1-323): 0: 579: 90.66		SNCAP_HUMAN (1-919): 0: 561: 100.00
+	Hs
		967671 PP1A_HUMAN (1-323): 0: 579: 90.66		ANK2_HUMAN (193-789): 1.79e-87: 309: 12.16
+	Hs
		967838 PP1A_HUMAN (1-323): 0: 579: 90.66		MIB1_HUMAN (309-636): 1e-47: 186: 13.27
+	Hs
		786728 PP1G_HUMAN (1-323): 0: 603: 100.00		ANR42_HUMAN (274-578): 1.34e-30: 126: 18.75
+	Hs
		50273 PP1G_HUMAN (1-323): 0: 603: 100.00		A1DRY3_HUMAN (274-557): 2.59e-27: 121: 18.12
+	Hs
		50274 PP1A_HUMAN (1-323): 0: 579: 90.66		A1DRY3_HUMAN (274-557): 2.59e-27: 121: 18.12
+	Hs
		786828 PP1G_HUMAN (1-323): 0: 603: 100.00		UACA_HUMAN (207-439): 3.52e-18: 92.3: 12.03
+	Mm
		968091 PP1A_MOUSE (1-323): 0: 579: 90.36		PP12C_MOUSE (245-453): 2.86e-21: 101: 14.74
+	Hs
		968432 PP1B_HUMAN (1-322): 0: 560: 86.89		UACA_HUMAN (207-439): 3.52e-18: 92.3: 12.03
+	Hs
		920423 PP2AA_HUMAN (8-312): 5.37e-178: 496: 46.08		DAPK1_HUMAN (212-439): 9.66e-37: 152: 17.60