HitPredict

Interactor 1: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Interactor 2: RPN8 (Q08723)
26S proteasome regulatory subunit RPN8
Gene: RPN8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.916

Property	Details
Experiments	16554755, 31487956, 23900548, 37968396, 14759368
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~Prot_ATP_ID_OB, MitMem_reg~Prot_ATP_ID_OB
Common GO terms	GO:0000502 - proteasome complex GO:0034515 - proteasome storage granule GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 405 Sc			1 338
+	At
		1320084 PRS4A_ARATH (11-395): 5.61e-138: 403: 44.16		PSD7B_ARATH (6-311): 1.9e-100: 300: 49.03
+	At
		188943 PRS4A_ARATH (11-395): 5.61e-138: 403: 44.16		PSD7A_ARATH (6-308): 6.55e-100: 298: 49.18
+	Dm
		186102 PRS8_DROME (1-405): 2.81e-131: 384: 73.83		PSMD7_DROME (4-325): 8.23e-103: 307: 45.68
+	Hs
		849177 PRS8_HUMAN (3-405): 1.36e-129: 380: 73.95		PSMD7_HUMAN (6-301): 2.63e-97: 292: 50.51
+	Dm
		640797 Q9W414_DROME (1-402): 3.17e-123: 364: 43.28		PSMD7_DROME (4-325): 8.23e-103: 307: 45.68
+	Sc
		771745 PRS4_YEAST (72-395): 3.99e-106: 321: 49.85		RPN8_YEAST (1-338): 6.52e-119: 348: 100.00
+	Dm
		640769 PRS4_DROME (2-395): 3.49e-118: 352: 43.40		PSMD7_DROME (4-325): 8.23e-103: 307: 45.68
+	Dm
		640783 Q9V405_DROME (5-397): 1.09e-118: 352: 39.50		PSMD7_DROME (4-325): 8.23e-103: 307: 45.68
+	Hs
		849179 PRS10_HUMAN (20-402): 2.79e-124: 366: 43.34		PSMD7_HUMAN (6-301): 2.63e-97: 292: 50.51
+	Sp
		251475 PRS10_SCHPO (25-403): 1.96e-159: 455: 43.95		RPN11_SCHPO (1-263): 3.34e-61: 199: 19.11
+	Hs
		849176 PRS4_HUMAN (2-395): 3.16e-121: 360: 44.92		PSMD7_HUMAN (6-301): 2.63e-97: 292: 50.51
+	Hs
		798615 PRS6B_HUMAN (13-397): 3.38e-118: 351: 41.04		PSMD7_HUMAN (6-301): 2.63e-97: 292: 50.51
+	Hs
		730219 PRS7_HUMAN (60-390): 7.87e-110: 331: 51.05		PSMD7_HUMAN (6-301): 2.63e-97: 292: 50.51
+	At
		1339598 PRS4A_ARATH (11-395): 5.61e-138: 403: 44.16		PSDE_ARATH (3-263): 1.25e-46: 161: 17.65
+	Sp
		784711 PRS8_SCHPO (21-405): 3.2e-123: 364: 77.20		RPN11_SCHPO (1-263): 3.34e-61: 199: 19.11
+	Dm
		186131 PRS8_DROME (1-405): 2.81e-131: 384: 73.83		PSDE_DROME (3-264): 6.45e-48: 165: 16.90
+	Dm
		1358678 Q9W414_DROME (1-402): 3.17e-123: 364: 43.28		PSDE_DROME (3-264): 6.45e-48: 165: 16.90
+	Dm
		1358669 Q9V405_DROME (5-397): 1.09e-118: 352: 39.50		PSDE_DROME (3-264): 6.45e-48: 165: 16.90
+	Dm
		820501 PRS4_DROME (2-395): 3.49e-118: 352: 43.40		PSDE_DROME (3-264): 6.45e-48: 165: 16.90
+	Dm
		1181024 Q7KMQ0_DROME (60-390): 1.44e-108: 327: 51.05		PSDE_DROME (3-264): 6.45e-48: 165: 16.90