Protein: SNCAP
Synphilin-1 (Sph1) (Alpha-synuclein-interacting protein)

Gene: SNCAP, SNCAIP
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q9Y6H5

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008021 - synaptic vesicle
GO:0008219 - cell death

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1491842

SNCAP
Synphilin-1

3

17

Small-scale

0.870

High

791883

SYUA
Alpha-synuclein

11

2

Small-scale

0.761

High

243448

PRKN
E3 ubiquitin-protein ligase parkin

9

10

Small-scale

0.752

High

238834

KALRN
Kalirin

1

20

Small-scale

0.740

High

891925

GSK3B
Glycogen synthase kinase-3 beta

1

9

Small-scale

0.724

High

998142

CSK21
Casein kinase II subunit alpha

1

5

Small-scale

0.724

High

786963

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

4

10

Small-scale

0.698

High

1123188

FHL2
Four and a half LIM domains protein 2

1

10

High-throughput

0.691

High

1307825

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

8

Small-scale

0.660

High

1417123

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

Small-scale

0.621

High

211609

SIAH2
E3 ubiquitin-protein ligase SIAH2

2

8

Small-scale

0.619

High

851453

PRS6B
26S proteasome regulatory subunit 6B

1

5

Small-scale

0.618

High

1114788

CUL3
Cullin-3

1

19

High-throughput

0.618

High

1458578

HDAC6
Protein deacetylase HDAC6

1

8

Small-scale

0.618

High

968058

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

2

10

Small-scale

0.595

High

1491509

NUB1
NEDD8 ultimate buster 1

2

0

Small-scale

0.593

High

1199777

KLH22
Kelch-like protein 22

1

3

High-throughput

0.575

High

1450250

RN19A
E3 ubiquitin-protein ligase RNF19A

1

3

Small-scale

0.561

High

1429560

RB33B
Ras-related protein Rab-33B

1

4

High-throughput

0.553

High

1338195

PPHLN
Periphilin-1

1

1

Small-scale

0.552

High

1109432

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

Small-scale

0.537

High

1383802

TTC28
Tetratricopeptide repeat protein 28

1

7

High-throughput

0.536

High

1434425

RNF41
E3 ubiquitin-protein ligase NRDP1

1

14

High-throughput

0.536

High

1272452

GET4
Golgi to ER traffic protein 4 homolog

1

0

High-throughput

0.518

High

228404

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.486

High

1327823

SH2D3
SH2 domain-containing protein 3C

1

16

High-throughput

0.481

High

1049957

1433F
14-3-3 protein eta

1

20

Small-scale

0.479

High

1133079

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

High-throughput

0.479

High

1156368

SYUB
Beta-synuclein

1

2

Small-scale

0.479

High

1491469

ARI1
E3 ubiquitin-protein ligase ARIH1

1

9

Small-scale

0.479

High

638865

AGT1
Alanine--glyoxylate aminotransferase

1

1

High-throughput

0.457

High

1404557

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.457

High

982381

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

9

Small-scale

0.445

High

1061932

TLE5
TLE family member 5

1

3

High-throughput

0.417

High

636786

PTN
Pleiotrophin

1

0

High-throughput

0.282

High

1233898

K0930
Uncharacterized protein KIAA0930

1

0

High-throughput

0.279

Low

125977

SMAP
Small acidic protein

1

0

High-throughput

0.265

Low

1136709

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025