HitPredict

Interactor 1: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR

Interactor 2: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30948266
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043066 - negative regulation of apoptotic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 2549 Hs			1 604
+	Hs
		1035697 ATR_HUMAN (186-2548): 0: 816: 14.82		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Hs
		944227 PRKDC_HUMAN (695-2548): 0: 686: 14.83		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Hs
		1035936 GCN1_HUMAN (245-1372): 1.05e-38: 162: 12.17		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Hs
		177669 PRKDC_HUMAN (695-2548): 0: 686: 14.83		BIRC5_HUMAN (258-332): 1.39e-25: 104: 35.00