HitPredict

Interactor 1: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Interactor 2: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25659891, 32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 896 Hs			1 603
+	Hs
		861770 ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		861960 EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		160427 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17
+	At
		1104938 EHD1_ARATH (1-453): 2.72e-37: 149: 16.46		CDPK4_ARATH (32-529): 7.24e-158: 463: 20.87
+	Hs
		1071723 MRCKB_HUMAN (223-886): 2.4e-41: 167: 12.72		KS6A2_HUMAN (1-367): 4.14e-105: 335: 22.43
+	Hs
		160824 EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17