Protein: PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)]

Gene: PLOD3
Organism: Homo sapiens
Interactions: 150
UniProt ID: O60568

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0001886 - endothelial cell morphogenesis
GO:0005506 - iron ion binding
GO:0005615 - extracellular space
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

237047

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

2

10

Small-scale

0.799

High

237003

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

2

10

Small-scale

0.755

High

129872

PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

1

10

High-throughput

0.691

High

237108

EHMT2
Histone-lysine N-methyltransferase EHMT2

6

2

Small-scale

0.672

High

237008

ESR1
Estrogen receptor

3

1

High-throughput

0.624

High

237051

CUL3
Cullin-3

2

6

High-throughput

0.611

High

237139

COHA1
Collagen alpha-1(XVII) chain

2

20

High-throughput

0.606

High

237127

FBX6
F-box only protein 6

3

6

High-throughput

0.599

High

237080

CRIP3
Cysteine-rich protein 3

2

0

High-throughput

0.580

High

237082

ZN620
Zinc finger protein 620

2

0

High-throughput

0.580

High

237031

HNRH1
Heterogeneous nuclear ribonucleoprotein H

2

6

High-throughput

0.574

High

237039

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

2

6

High-throughput

0.574

High

237010

P53
Cellular tumor antigen p53

2

2

Small-scale

0.571

High

237006

CO4A1

1

20

High-throughput

0.536

High

237007

C1QA
Complement C1q subcomponent subunit A

1

20

High-throughput

0.536

High

237015

MMP2
72 kDa type IV collagenase

1

2

High-throughput

0.536

High

237016

CO4A2

1

20

High-throughput

0.536

High

237019

CO6A1

1

20

High-throughput

0.536

High

237020

CO6A2

1

20

High-throughput

0.536

High

237021

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

237024

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

1

High-throughput

0.536

High

237029

PML
Protein PML

1

1

High-throughput

0.536

High

237034

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

20

High-throughput

0.536

High

237041

PCBP3
Poly(rC)-binding protein 3

1

1

High-throughput

0.536

High

237045

C1QT8
Complement C1q tumor necrosis factor-related protein 8

1

20

High-throughput

0.536

High

237048

COGA1

1

20

High-throughput

0.536

High

237052

CO4A6

1

20

High-throughput

0.536

High

237053

CO9A3

1

20

High-throughput

0.536

High

237054

CO9A2

1

20

High-throughput

0.536

High

237075

CODA1
Collagen alpha-1(XIII) chain

1

20

High-throughput

0.536

High

237076

SCAR3
Scavenger receptor class A member 3

1

20

High-throughput

0.536

High

237090

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

237091

CONA1

1

20

High-throughput

0.536

High

237094

GT252
Procollagen galactosyltransferase 2

1

10

High-throughput

0.536

High

237097

GT251
Procollagen galactosyltransferase 1

1

10

High-throughput

0.536

High

237111

COLA1

1

20

High-throughput

0.536

High

237114

COCA1

1

19

High-throughput

0.536

High

237116

COL11
Collectin-11

1

20

High-throughput

0.536

High

237117

C1QT6
Complement C1q tumor necrosis factor-related protein 6

1

20

High-throughput

0.536

High

237118

C1QT1
Complement C1q tumor necrosis factor-related protein 1

1

20

High-throughput

0.536

High

237120

VP33B
Vacuolar protein sorting-associated protein 33B

1

1

High-throughput

0.536

High

237124

SPE39
Spermatogenesis-defective protein 39 homolog

1

1

High-throughput

0.536

High

237137

FBX2
F-box only protein 2

1

6

High-throughput

0.536

High

237140

COLQ
Acetylcholinesterase collagenic tail peptide

1

20

High-throughput

0.536

High

237141

COL10
Collectin-10

1

20

High-throughput

0.536

High

237115

RHXF2
Rhox homeobox family member 2

1

1

High-throughput

0.532

High

237026

CATS
Cathepsin S

1

3

High-throughput

0.515

High

237133

MARCO
Macrophage receptor MARCO

1

20

High-throughput

0.515

High

237049

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.513

High

237068

FWCH1
FLYWCH-type zinc finger-containing protein 1

1

0

High-throughput

0.513

High

237084

RHOU
Rho-related GTP-binding protein RhoU

1

6

High-throughput

0.501

High

237069

MBRL
Membralin

1

0

High-throughput

0.493

High

70492

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

20

High-throughput

0.489

High

237004

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.489

High

237060

EPHA7
Ephrin type-A receptor 7

1

9

High-throughput

0.489

High

237073

PRC2B
Protein PRRC2B

1

1

High-throughput

0.489

High

237077

LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

1

1

High-throughput

0.489

High

237079

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

1

High-throughput

0.489

High

237107

RITA1
RBPJ-interacting and tubulin-associated protein 1

1

2

High-throughput

0.489

High

204800

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

216122

CALU
Calumenin

1

3

High-throughput

0.479

High

226002

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

237013

CATL1
Procathepsin L

1

3

High-throughput

0.479

High

237014

CATB
Cathepsin B

1

5

High-throughput

0.479

High

237017

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

3

High-throughput

0.479

High

237018

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.479

High

237022

PDIA4
Protein disulfide-isomerase A4

1

7

High-throughput

0.479

High

237027

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.479

High

237028

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

237035

VHL
von Hippel-Lindau disease tumor suppressor

1

2

Small-scale

0.479

High

237042

SC61B
Protein transport protein Sec61 subunit beta

1

3

High-throughput

0.479

High

237050

DNJC3
DnaJ homolog subfamily C member 3

1

13

High-throughput

0.479

High

237057

EMC2
ER membrane protein complex subunit 2

1

2

High-throughput

0.479

High

237064

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

3

High-throughput

0.479

High

237065

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

4

High-throughput

0.479

High

237067

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

237081

SYNE3
Nesprin-3

1

3

High-throughput

0.479

High

237092

DJC10
DnaJ homolog subfamily C member 10

1

14

High-throughput

0.479

High

237093

YAF2
YY1-associated factor 2

1

1

High-throughput

0.479

High

237096

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.479

High

237099

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

237102

LRC59
Leucine-rich repeat-containing protein 59

1

3

High-throughput

0.479

High

237109

CALR3
Calreticulin-3

1

7

High-throughput

0.479

High

237129

DJB12
DnaJ homolog subfamily B member 12

1

9

High-throughput

0.479

High

237130

VAPA
Vesicle-associated membrane protein-associated protein A

1

3

High-throughput

0.479

High

237131

DNJB9
DnaJ homolog subfamily B member 9

1

12

High-throughput

0.479

High

237132

DJB11
DnaJ homolog subfamily B member 11

1

3

High-throughput

0.479

High

237134

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

57013

A2ABF9
Euchromatic histone lysine methyltransferase 2

1

2

High-throughput

0.470

High

237070

Q53GL6
RNA binding protein

1

1

High-throughput

0.470

High

237043

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

0

High-throughput

0.458

High

237089

CLC14
C-type lectin domain family 14 member A

1

0

Small-scale

0.458

High

237101

REQU
Zinc finger protein ubi-d4

1

0

High-throughput

0.458

High

237122

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

237005

CO1A1
Collagen alpha-1(I) chain

1

20

Small-scale

0.445

High

237044

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

6

High-throughput

0.445

High

237119

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

6

High-throughput

0.445

High

237138

RALY
RNA-binding protein Raly

1

1

High-throughput

0.439

High

233091

NUPR1
Nuclear protein 1

1

2

High-throughput

0.437

High

237009

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

237011

ISG15
Ubiquitin-like protein ISG15

1

1

High-throughput

0.437

High

237023

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

237038

EFNA4
Ephrin-A4

1

6

High-throughput

0.437

High

237055

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.437

High

237058

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.437

High

237059

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.437

High

237063

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

237074

EPHAA
Ephrin type-A receptor 10

1

9

High-throughput

0.437

High

237078

TECT3
Tectonic-3

1

5

High-throughput

0.437

High

237083

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

237098

FBX22
F-box only protein 22

1

1

High-throughput

0.437

High

237103

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.437

High

237104

AURKB
Aurora kinase B

1

1

High-throughput

0.437

High

237105

TECT2
Tectonic-2

1

5

High-throughput

0.437

High

237110

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

12

High-throughput

0.437

High

237123

WDR76
WD repeat-containing protein 76

1

1

High-throughput

0.437

High

237125

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.437

High

237128

T106B
Transmembrane protein 106B

1

4

High-throughput

0.437

High

237121

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

6

High-throughput

0.407

High

237072

EFHC2
EF-hand domain-containing family member C2

6

0

High-throughput

0.386

High

237112

RAB3I
Rab-3A-interacting protein

4

0

High-throughput

0.370

High

165305

KHNYN
Protein KHNYN

2

0

High-throughput

0.316

High

235450

VINEX
Vinexin

2

0

High-throughput

0.316

High

237033

COIL
Coilin

2

0

High-throughput

0.316

High

237061

NAB2
NGFI-A-binding protein 2

2

0

High-throughput

0.316

High

237085

KCTD9
BTB/POZ domain-containing protein KCTD9

2

0

High-throughput

0.316

High

237106

LMBL3
Lethal(3)malignant brain tumor-like protein 3

2

0

High-throughput

0.316

High

237135

IP6K2
Inositol hexakisphosphate kinase 2

2

0

High-throughput

0.316

High

237126

ANLN
Anillin

2

0

High-throughput

0.305

High

237062

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.282

High

237087

DPPA2
Developmental pluripotency-associated protein 2

1

0

High-throughput

0.282

High

237037

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.279

Low

237046

RBM6
RNA-binding protein 6

1

0

High-throughput

0.279

Low

237066

GEN
Flap endonuclease GEN homolog 1

1

0

High-throughput

0.279

Low

237071

KLH22
Kelch-like protein 22

1

0

High-throughput

0.279

Low

237086

TCPR1
Tectonin beta-propeller repeat-containing protein 1

1

0

High-throughput

0.279

Low

237088

LYG2
Lysozyme g-like protein 2

1

0

High-throughput

0.279

Low

237095

THNS1
Threonine synthase-like 1

1

0

High-throughput

0.279

Low

237100

PRCC
Proline-rich protein PRCC

1

0

High-throughput

0.279

Low

224732

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

0

High-throughput

0.269

Low

237136

F153A
Protein FAM153A

1

0

High-throughput

0.251

Low

237012

NFM
Neurofilament medium polypeptide

1

0

High-throughput

0.249

Low

237025

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.249

Low

237030

CCND2
G1/S-specific cyclin-D2

1

0

Small-scale

0.249

Low

237032

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.249

Low

237036

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.249

Low

237056

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.249

Low

237040

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.232

Low

237113

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024