Interactor 1: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Interactor 2: PICAL (Q13492)
Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein)
Gene: PICALM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.670

The method score is based on:

Property Details
Experiments 26496610, 28514442, 35044719
Identification Methods affinity chromatography technology, unspecified method, anti tag coimmunoprecipitation, phage display
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005905 - clathrin-coated pit
GO:0006897 - endocytosis
GO:0016020 - membrane
and 5 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 896
Hs

1 652
+ Hs
+ Rn
+ Hs
+ Hs
+ Ce
+ Hs
+ Sc
+ Sc
+ Hs
+ Sc
+ Sc
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024