HitPredict

Interactor 1: RL35 (P42766)
Large ribosomal subunit protein uL29 (60S ribosomal protein L35)
Gene: RPL35

Interactor 2: DDX18 (Q9NVP1)
ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)
Gene: DDX18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 123 Hs			1 670
+	Hs
		790384 RL35_HUMAN (1-123): 5.55e-34: 115: 100.00		DDX10_HUMAN (124-621): 9.53e-167: 501: 41.60
+	Sc
		482929 RL35A_YEAST (1-123): 9.6e-26: 95.2: 56.10		HAS1_YEAST (142-641): 8.13e-140: 420: 57.69
+	Sc
		482826 RL35A_YEAST (1-123): 9.6e-26: 95.2: 56.10		DBP2_YEAST (75-553): 1.02e-125: 385: 24.29
+	Hs
		790563 RL35_HUMAN (1-123): 5.55e-34: 115: 100.00		DDX31_HUMAN (87-619): 1.02e-81: 278: 33.71
+	Hs
		790511 RL35_HUMAN (1-123): 5.55e-34: 115: 100.00		DDX27_HUMAN (121-574): 3.56e-56: 206: 34.88