HitPredict

Interactor 1: SYNJ1 (O43426)
Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)
Gene: SYNJ1

Interactor 2: PACN3 (Q9UKS6)
Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511)
Gene: PACSIN3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11082044
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1573 Hs			1 424
+	Hs
		215948 SYNJ1_HUMAN (1-1573): 0: 1388: 100.00		PACN1_HUMAN (4-422): 1.2e-86: 272: 48.86
+	Hs
		215960 SYNJ1_HUMAN (1-1573): 0: 1388: 100.00		PACN2_HUMAN (4-422): 1.77e-78: 252: 48.96
+	Hs
		215920 SYNJ1_HUMAN (1-1573): 0: 1388: 100.00		MYO1E_HUMAN (35-422): 2.55e-39: 152: 14.42
+	Hs
		215925 SYNJ1_HUMAN (1-1573): 0: 1388: 100.00		ITSN1_HUMAN (346-421): 2.69e-15: 80.6: 28.95
+	Hs
		215943 SYNJ1_HUMAN (1-1573): 0: 1388: 100.00		SH3Y1_HUMAN (308-419): 5.43e-12: 68.7: 24.78
+	Hs
		176266 SYNJ2_HUMAN (1-1418): 0: 1121: 42.03		ITSN1_HUMAN (346-421): 2.69e-15: 80.6: 28.95
+	Sc
		850445 INP52_YEAST (8-1106): 0: 838: 26.08		LSB3_YEAST (312-422): 8.7e-13: 71.8: 25.89
+	Sc
		850508 INP53_YEAST (33-1085): 0: 832: 26.86		LSB3_YEAST (312-422): 8.7e-13: 71.8: 25.89
+	Sc
		805451 INP53_YEAST (33-1085): 0: 832: 26.86		BZZ1_YEAST (1-248): 2.88e-12: 70.6: 19.17
+	Mm
		1021933 SHIP1_MOUSE (505-1251): 6.67e-154: 502: 20.90		PPIP1_MOUSE (7-422): 1.18e-64: 215: 20.37
+	Hs
		1150885 SHIP1_HUMAN (505-1301): 6.07e-139: 462: 21.40		CIP4_HUMAN (16-366): 1.88e-38: 148: 15.34
+	Hs
		1033971 OCRL_HUMAN (502-978): 1.76e-124: 414: 27.52		MYO1E_HUMAN (35-422): 2.55e-39: 152: 14.42