HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 727
+	Hs
		297587 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RHBT1_HUMAN (1-708): 6.34e-160: 480: 67.65
+	Hs
		790730 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		893947 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		894594 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		1021431 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		ABTB2_HUMAN (231-647): 1.15e-77: 271: 17.08
+	Hs
		545247 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RAC2_HUMAN (12-219): 9.54e-73: 236: 36.97
+	Hs
		790729 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RAC3_HUMAN (12-208): 3.69e-72: 234: 39.50
+	Hs
		790746 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		790732 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29
+	Hs
		564741 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RHOQ_HUMAN (10-225): 1.24e-84: 267: 36.53
+	Hs
		925204 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		925238 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		950953 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		900423 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29
+	Hs
		214374 EHMT1_HUMAN (4-121): 1.19e-30: 117: 19.33		SPOP_HUMAN (305-670): 2.13e-72: 241: 13.30
+	Hs
		892683 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RAC3_HUMAN (12-208): 3.69e-72: 234: 39.50
+	Hs
		925737 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		951461 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		901057 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29
+	Hs
		914463 ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59		RB11A_HUMAN (5-252): 2.31e-70: 230: 16.34