HitPredict

Interactor 1: NOP4 (P37838)
Nucleolar protein 4 (Nucleolar protein NOP77)
Gene: NOP4

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	11805826, 16429126, 16287855, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 685 Sc			1 291
+	Sc
		782313 NOP4_YEAST (1-685): 7.18e-109: 346: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		791055 NOP4_YEAST (1-685): 7.18e-109: 346: 100.00		RPF1_YEAST (4-252): 5.86e-52: 173: 14.40
+	Sc
		791053 NOP4_YEAST (1-685): 7.18e-109: 346: 100.00		SSF1_YEAST (10-197): 9.09e-34: 129: 15.64
+	Sc
		403678 PABP_YEAST (489-600): 1.5e-11: 69.4: 12.50		BRX1_YEAST (1-291): 1.12e-99: 295: 100.00
+	Dm
		1489009 Q9W124_DROME (15-105): 4.39e-10: 65: 18.68		BRX1_DROME (8-291): 5.4e-82: 253: 40.91
+	Hs
		1435609 RBM28_HUMAN (2-293): 2.51e-13: 75.4: 15.54		RPF2_HUMAN (1-285): 3.54e-77: 238: 17.57
+	Sc
		403457 PABP_YEAST (489-600): 1.5e-11: 69.4: 12.50		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Dm
		1472572 Q9W124_DROME (15-105): 4.39e-10: 65: 18.68		RPF2_DROME (3-288): 1.61e-60: 196: 16.67
+	Hs
		1446766 RBM28_HUMAN (2-293): 2.51e-13: 75.4: 15.54		SSF1_HUMAN (12-281): 5.7e-45: 160: 12.87
+	Dm
		1471510 Q9W124_DROME (15-105): 4.39e-10: 65: 18.68		PPAN_DROME (6-248): 5.22e-26: 108: 13.77