HitPredict

Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	32814053, 17500595
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 3142 Hs			1 548
+	Hs
		791372 HD_HUMAN (1-3142): 0: 5724: 100.00		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		573161 HD_HUMAN (1-3142): 0: 5724: 100.00		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Mm
		102855 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		TCPQ_MOUSE (1-548): 0: 617: 96.90
+	Mm
		102973 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		TCPH_MOUSE (9-546): 0: 573: 26.92
+	Mm
		102978 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		TCPG_MOUSE (10-547): 0: 557: 27.66
+	Mm
		102975 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		TCPD_MOUSE (2-525): 0: 536: 27.90
+	Mm
		102976 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		TCPE_MOUSE (2-524): 0: 529: 29.06
+	Mm
		102760 G3X9H5_MOUSE (81-3142): 0: 5479: 91.19		TCPA_MOUSE (31-529): 2e-67: 229: 30.71